The NanoTherm® Therapy System (NTTS) is a set of medical devices approved for use in the EU for the focal treatment of recurrent glioblastoma.

Magnetic nanoparticles are introduced either directly into the tumor or onto the resection cavity wall. These particles convert energy from an external alternating magnetic field into heat, causing the temperature in the tissue to rise in a controlled manner. Temperature can destroy cancer cells or weaken them to be made more sensitive for radiotherapy or chemotherapy. The surrounding healthy tissue is spared.